Spinal muscular Atrophy (SMA) is a group of genetic diseases that cause muscle weakness and wasting (atrophy) due to the loss of specialized nerve cells called motor neurons. These motor neurons, located in the spinal cord and brainstem, are crucial for controlling voluntary muscle movements like walking, breathing, and swallowing. SMA is primarily caused by mutations in the SMN1 gene, which lead to a deficiency in the SMN protein, essential for motor neuron survival and function. Key aspects of

The NICE Guideline on motor neurone disease has been developed to ensure that the needs of those living with the disease are met. Watch our animated video below for more information. You can also visit our website for lots more information including what do do if your needs are not being met 👩‍⚕️ mndassociation.org/nice. | MND Association