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  1. Pepsin - Wikipedia

    Pepsin is an aspartic protease, using a catalytic aspartate in its active site. [2] It is one of three principal endopeptidases (enzymes cutting proteins in the middle) in the human digestive system, the other …

  2. Pepsin | Description, Production, & Function | Britannica

    Pepsin is a powerful enzyme in gastric juice that digests proteins such as those in meat, seeds, and dairy products. It is the mature active form of pepsinogen, which is released into the stomach and …

  3. Pepsin: Signs You Need This Vital Enzyme and How to Get It - Dr. Axe

    Nov 5, 2018 · The definition of pepsin is a digestive enzyme in the stomach that breaks down proteins into smaller units called polypeptides (or peptides for short). This enzyme helps digest proteins — …

  4. Where Does Pepsin Come From and What Does It Do?

    Aug 19, 2025 · Pepsin is a digestive enzyme found in the stomach, breaking down proteins from the food we eat. It functions as an endopeptidase, meaning it cleaves peptide bonds within protein …

  5. Pepsin digestive enzyme benefits, uses, dosage, and safety guide

    Dec 8, 2025 · What is pepsin and how it works Pepsin is an aspartic protease, a type of protein cutting enzyme, produced by chief cells in the lining of the stomach. These cells secrete pepsin in an …

  6. PDB-101: Molecule of the Month: Pepsin

    Our digestive system contains a host of tough, stable enzymes designed to seek out those rich holiday treats and break them into small pieces. Pepsin is the first in a series of enzymes that digest proteins.

  7. Physiology of Pepsin: Unleashing the Power of Protein Digestion

    Pepsin is a critical enzyme involved in the digestion of proteins in the stomach. This article explores the physiology of pepsin, including its synthesis, activation, and the role it plays in protein digestion and …

  8. Rethinking Reflux: The Real Culprit Isn’t Acid—It’s Pepsin

    Feb 24, 2025 · At-A-Glance The digestive enzyme pepsin, not acid, is the primary culprit behind reflux-related damage. Unlike acid, pepsin sticks to tissues in the throat and airways, reactivating with …

  9. Physiology, Pepsin - PubMed

    May 1, 2023 · Of these five components, pepsin is the principal enzyme involved in protein digestion. It breaks down proteins into smaller peptides and amino acids that can be easily absorbed in the small …

  10. Pepsin - an overview | ScienceDirect Topics

    Pepsin is defined as a powerful enzyme present in gastric juice that aids in the digestion of complex food particles, produced from its proenzyme pepsinogen through reaction with hydrochloric acid (HCl) in …