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  1. Smallpox - Wikipedia

    Smallpox was an infectious disease caused by Variola virus (often called Smallpox virus), which belongs to the genus Orthopoxvirus. [7][11] The last naturally occurring case was diagnosed in October 1977, …

  2. Smallpox | Definition, History, Vaccine, & Facts | Britannica

    Nov 27, 2025 · Smallpox is an infectious disease that begins with fever and headache and proceeds to an eruption of the skin that leaves pockmarks. For centuries smallpox was one of the world’s most …

  3. Smallpox - World Health Organization (WHO)

    Nov 14, 2024 · Smallpox is an acute contagious disease caused by the variola virus, a member of the orthopoxvirus family. It was one of the most devastating diseases known to humanity and caused …

  4. About Smallpox | Smallpox | CDC

    Oct 22, 2024 · Smallpox was a serious infectious disease caused by variola virus. The disease has been eradicated.

  5. Smallpox: Causes, Symptoms, Treatment & Prevention

    Apr 7, 2023 · What do 18th century milkmaids and modern vaccines have in common? Learn more about smallpox, the deadly disease we successfully rid from the world.

  6. Smallpox - Symptoms and causes - Mayo Clinic

    Aug 5, 2022 · Smallpox is a serious and often deadly viral infection. It's contagious — meaning it spreads from person to person — and can cause permanent scarring. Sometimes, it causes …

  7. Smallpox - HealthLink BC

    Smallpox is a contagious infection caused by the variola virus. Smallpox can be deadly, so if an outbreak happens, it is vital to stay away from infected people.

  8. Smallpox Information and Facts - National Geographic

    Smallpox is an acute contagious disease caused by the variola virus. It gets its name from the Latin word for "spotted," referring to the raised, pustular bumps that break out over the face and ...

  9. Smallpox: Causes, Symptoms, & Vaccines - WebMD

    Jan 31, 2024 · Smallpox is a serious infectious disease caused by a virus that’s no longer found in nature. It was passed from person to person. People with smallpox had flu-like symptoms and a rash …

  10. Smallpox - Infectious Diseases - Merck Manual Professional Edition

    Smallpox is a highly contagious disease caused by the smallpox virus, an orthopoxvirus. Case fatality rate is about 30%. Natural infection has been eradicated. The main concern for outbreaks is from …