USA TODAY readers have spoken – and they want a third party in US politics. But is Elon Musk the one to lead it?

Tyrese Haliburton will have no problem staying busy while he recovers from an Achilles tendon tear. Among other things, he'll be planning a wedding.

Phase 1 results demonstrate that SUL-238, a first-in-class, orally administered, mitochondria-directed drug candidate, is ...

After a shooting left his brother in critical condition and a bullet in his spine, James Holder says he now wants to move after neighbor's arrest.

Parents and schools brace for Indiana’s new reading law, which may hold back more third graders—just as summer school funding ...

Democrats notched a big win with their recruitment of Roy Cooper for the open Senate seat being vacated by Republican Sen. Thom Tillis.

The Department of Justice is scrutinizing how battleground states manage voter rolls, focusing on removing ineligible voters.

Athlete consultant and promoter Amp Harris saw his stepdad shoot his brother. The moment made a man whose legacy in Indianapolis is in incomparable.

The air was heavy with the threat of rain and bad QB play, but Mother Nature – and Anthony Richardson and Daniel Jones – flipped script at Colts camp.

Kelsey Mitchell is third in the WNBA in scoring, in large part to her offseason training... doing defensive back drills on a football field.

Lee Zeldin, the head of the EPA, is set to visit Indianapolis to announce a major environmental policy change. Some say it may rollback key climate finding.

WESTFIELD, Ind. — The quarterback battle between Anthony Richardson and Daniel Jones took a turn for the better on Monday, the first day of full pads in Colts training camp.