"We're doing what we need to do," Israeli PM Benjamin Netanyahu tells Jon Karl about the possibility of taking out Iran's Supreme Leader while discussing the conflict with Iran.

As tensions rise after Israeli airstrikes on Iran's nuclear sites, Prime Minister Netanyahu accused Iran of plotting against the U.S. president.

Since Israel began its concerted attack on Iran on Friday, calls for regime change in Iran have grown louder – from hawks in the US Congress to Israeli officials and some Iranian activists abroad.

Israeli Prime Minister Benjamin Netanyahu is on the mission of his lifetime. For years, the veteran leader has made the destruction of Iran’s nuclear program his top priority.

Khamenei has condemned the attacks and promised to retaliate, saying Israel had "sealed for itself a bitter and painful destiny."

Israeli Prime Minister Benjamin Netanyahu expressed support for killing Iran’s Supreme Leader Ali Khamenei to end their ongoing military conflict, despite President Trump reportedly

Israeli PM Netanyahu compared Iran's nuclear program to cancer, vowing it must be "cut out." He said Israel will destroy Iran's nuclear, missile, and terror infrastructure, with US support. He also hinted the Iranian regime could collapse under pressure,

Lapid made a speech last month to Israel’s parliament, which is called the Knesset, that marked 600 days since the start of the war in Gaza. Lapid slammed Netanyahu for bringing a conflict upon Israel that didn’t exist during his own brief time in office.

Israeli Prime Minister Benjamin Netanyahu was coy about whether the ultimate goal of the preemptive strikes on Iran is a regime change, but made clear that such a powershift would be a welcome outcome.

The Israelis had the opportunity to assassinate Supreme Leader Ayatollah Ali Khamenei and President Trump conveyed to Prime Minister Benjamin Netanyahu that it wasn't a good idea, one U.S. official told CBS News.