A toxin produced by bacteria found in dirty water kills off immune cells in the lining of the colon, meaning people whose guts are colonised by these bacteria are much more likely to develop a ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Subcutaneous guselkumab induction and maintenance ...

Ulcerative colitis is a type of inflammatory bowel disease (IBD) that causes inflammation of the colon, and leads to symptoms such as fatigue, abdominal pain, and cramping. There is currently no cure ...

Findings showed 32% of patients achieved clinical remission (Mayo score ≤2 points, with no individual subscore >1) at week 6. The Food and Drug Administration (FDA) has expanded the approval of ...

A once-daily pill for ulcerative colitis has delivered strong results in a clinical trial, easing symptoms even in patients for whom other treatments had failed and raising hopes for a safer, more ...

Please provide your email address to receive an email when new articles are posted on . The FDA has approved golimumab for the treatment of children with moderately to severely active ulcerative ...

The FDA approved the TNF-alpha inhibitor golimumab (Simponi, Johnson & Johnson) to treat children with moderately to severely active ulcerative colitis (UC) weighing at least 15 kg. Of the more than 1 ...

Ustekinumab, a humanised monoclonal antibody, was well tolerated and demonstrated acceptable remission rates and drug persistence at 1 year in patients with refractory ulcerative colitis (UC). "This ...

CAR T-cell therapy was first developed as a lymphoma treatment but has recently been applied to autoimmune diseases, primarily lupus, systemic sclerosis, and myositis. Up to this point, ulcerative ...

With a fresh endorsement from the FDA, Johnson & Johnson has rounded out Tremfya’s presence in inflammatory bowel disease (IBD) and, in doing so, achieved a first for the IL-23 inhibitor drug class.

For decades, scientists have puzzled over why smoking makes Crohn’s disease worse but seems to protect people from ulcerative colitis. Now, researchers at RIKEN have discovered that smoking creates ...

Although more research is needed to understand how menopause may affect ulcerative colitis (UC), some studies suggest the rapid decline of hormones in menopause may worsen UC symptoms for some women. ...