This work describes a useful computational tool for automated morphometry of dynamic organelles from microscope images. However, the supporting evidence and novelty of the manuscript as presented are ...

This repository contains an ImageJ/FIJI macro used to assist part of the image analysis performed in the study: "Characterizing mitochondrial phenotypes and MERCS in aged human skeletal muscle ...

ABSTRACT: Purpose: Chronic kidney disease (CKD) profoundly affects bone metabolism, contributing to CKD-related mineral and bone disorder and secondary osteoporosis, which increases fracture risk.

The schematic illustrates the comprehensive pipeline for Mendelian randomization analysis, starting with multi-omics data inputs from GWAS, eQTL, and pQTL studies, sourced from major databases such as ...

Excessive pulmonary inflammation in acute lung injury (ALI) results in high patient mortality. Interleukin-1 receptor-associated kinase 4 (IRAK4) is a potential therapeutic target for inflammatory ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. No ...

Using a large proteomics database and a public dataset of 394,244 samples (21,617 COPD cases and 372,627 controls), 4,907 proteins were associated with COPD. Causality was assessed using Bayesian ...

Abstract: Accurate quantification of wound closure in cell migration assays is crucial yet challenging. Still, existing methods often underperform due to omitting cell detection within the wound area, ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. A common desire in nanoscience is to describe the size and morphology of nanoparticles ...