For more than a century, oral insulin has been considered a "dream" therapy for diabetes, hindered by enzymatic degradation in the digestive tract and the absence of a dedicated intestinal transport ...
Lysosomes are membrane-bound organelles whose acidic lumen (pH 4.5–5.0) is required for degradation. This luminal acidity is ...
Abiotic Stress and Plant Cytoskeleton Dynamics: Unraveling Structural Pathways for Stress Adaptation
Plants are increasingly encountering abiotic stressors, such as salinity, drought, heavy metals, microplastics, and various environmental contaminants, that ...
Following the hard-won success of early anti-amyloid drugs, a new generation of Alzheimer’s modalities—from tau-targeting ...
Maze Therapeutics uses its Compass genetics platform to advance kidney and obesity drugs, with MZE829 Phase 2 data due in ...
The blood-brain and blood-retinal barriers are protective systems that prevent harmful substances from entering the brain and ...
Abstract: Targeted drug delivery (TDD) has emerged as a promising strategy in cancer therapy, with nanoparticles playing a critical role in enhancing delivery precision and minimizing off-target ...
This illustration shows how the membrane trafficking protein VAMP72 gradually changed during plant evolution to give rise to VAMP727, which functions in transporting storage proteins to vacuoles. The ...
LEXINGTON, Mass., May 15, 2025 (GLOBE NEWSWIRE) -- Voyager Therapeutics, Inc. (Nasdaq: VYGR), a biotechnology company dedicated to leveraging genetics to treat neurological diseases, today announced ...
Department of Biochemistry and Cell Biology, State University of New York, Stony Brook, NY, United States Tobamovirus is a large group of positive-sense, single-stranded RNA viruses that cause ...
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