Early randomized clinical trials of aspirin and cancer, mostly involving middle-age adults, showed a reduced risk of cancer and lower cancer-related mortality, particularly for colorectal cancer (CRC) ...

A follow-up study suggests that aspirin therapy does not reduce cancer risk in older adults, but may instead increase ...

Low-dose aspirin may limit cancer metastasis by inhibiting platelet activation and enhancing T-cell immunity, supporting biomarker guided use while balancing bleeding risk overall.