SportsLine's model simulated Boston Celtics vs. Philadelphia 76ers 10,000 times and revealed its 2025 NBA Cup picks

The Boston Celtics will look to extend their first win streak of the NBA's 2025-26 regular season with a win against the Philadelphia 76ers.

The Boston Celtics and Philadelphia 76ers announced their starting lineups ahead of their opening Emirates NBA Cup game on Friday. The Celtics enter Friday's game on the back of two big wins after their 0-3 start to the season, and will look to keep moving in the right direction against their Atlantic Division rivals.

Preview the Philadelphia 76ers' NBA matchup with Boston, including betting odds, tips, trends, and game information.

The 76ers will be down a pair of rotation players as they face the Celtics at 7 p.m. Friday from Philadelphia. Paul George (left knee surgery) and Jared McCain (right thumb surgery) are both out for Friday’s contest as they have yet to play this season.

Can the 4-0 Philadelphia 76ers stay undefeated in the early stages of the 2024-25 NBA season? Their next test is a clash with the 2-3 Boston Celtics at 7 p.m. ET Friday night in a rematch of a game last week which Philly won 117-116 in Boston.

Tyrese Maxey had a great highlight during the third quarter of the 76ers' NBA Cup opener against the Celtics on Friday night.

Just a day removed from enacting their vengeance against the Philadelphia 76ers in another one-point nailbiter and winning their third straight game this season