The contrast between President Trump and Chicago-born Pope Leo XIV couldn’t be more stark, politically, personally, or in their world views.

While Pope Leo XIV presides over a flock of 1.4 billion people from within Vatican City, there’s one worldly responsibility he may not escape: Uncle Sam.

"I hope to be able to respond to [the challenges] with a healthy dialogue," said Cardinal Robert Prevost in 2023.

At a meeting Pope Leo held with international journalists, NBC News’ Lester Holt spent time speaking one-on-one with the Pontiff. They discussed the significance of the Pope being American and if he plans to return to the United States any time soon.

Pope Leo XIV is busy in his first full week of work in the Vatican, but will he consider making a trip home to Chicago in the near future?

On "This Week," Cardinal Cupich said Pope Leo XIV may call for changes to the United States immigration system.

Political figures around the world have congratulated Robert Francis Prevost, now known as Pope Leo XIV, after his election on Thursday, May 8, as Pontiff of the Roman Catholic Church. Hailing from Chicago and a dual U.

Louis Marius Prevost, the father of Pope Leo XIV, served on a D-Day landing ship during World War II and later became a junior lieutenant for the United States Navy.