Maternal genetic factors may reveal why pregnancy loss is so common

By studying genetic data from nearly 140,000 IVF embryos, scientists have with unprecedented detail revealed why fewer than ...
eLife

Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment

Single-cell transcriptomics identifies three discrete mouse trabecular meshwork subtypes and demonstrates that an Lmx1b glaucoma mutation drives mitochondrial dysfunction and elevated intraocular ...
Hosted on MSN

Lineage Cell Therapeutics receives iPSC line from Factor Bioscience

Lineage Cell Therapeutics (LCTX) announced the receipt of an induced pluripotent stem cell line containing hypoimmunity edits, from Factor Bioscience. Generation of the line marks a milestone in the ...
eLife

Replication stress-inducing ELF3 upregulation promotes BRCA1-deficient breast tumorigenesis in luminal progenitors

ELF3 axis enables luminal progenitor transformation in BRCA1-deficient breast cancer by reducing genomic instability and promoting progenitor identity.