Nature

‘Google for DNA’ brings order to biology’s big data

MetaGraph compresses vast data archives into a search engine for scientists, opening up new frontiers of biological discovery ...
ascopubs.org

Identification and Validation of Prognostic Model for Tumor Microenvironment-Associated Genes in Bladder Cancer Based on Single-Cell RNA Sequencing Data Sets

Combined Transcriptome and Circulating Tumor DNA Longitudinal Biomarker Analysis Associates With Clinical Outcomes in Advanced Solid Tumors Treated With Pembrolizumab The prognostic model demonstrated ...
Hosted on MSN

Advanced Statistical Method Reduces Noise in Single-Cell RNA-Sequencing Data

The world of cells is surprisingly noisy. Each cell carries unique genetic information, but when we try to measure cellular activity, signals can be lost or blurred, and differences between ...
AHA/ASA Journals

Single-Cell Splicing Isoform Atlas of the Adult Human Heart and Heart Failure

BACKGROUND: Alternative splicing plays crucial roles in normal heart development and cardiac disease by influencing protein-coding sequences, functional domains, and molecular networks. However, a ...
C&EN

Researchers can identify a person by sequencing RNA from individual cells

An individual’s genome is identifiable. But datasets of RNA sequences from single cells are like a blurry photocopy of the genome. The sequence numbers are small, the data are noisy, and the sequences ...