Cone snails deploy sophisticated venom cocktails to paralyse prey. Anthony King talks to the researchers harnessing these ...
In sum, the nonapeptide Oxytocin presents as a structurally well-defined peptide with a receptor system that is widely ...
Adhesion GPCRs are a large class of surface proteins that recognize chemical and mechanical stimuli in the body. The rapidly expanding body of knowledge on the therapeutic targeting of these receptors ...
In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug ...
Adhesion G protein-coupled receptors (GPCRs) are implicated in numerous human diseases. However, to date, no medicinal product has been approved that specifically targets these signalling molecules.
Deep mutational scanning reveals pharmacologically relevant insights into TYK2 signaling and disease
This important paper presents a rigorous and comprehensive deep mutational analysis of the kinase TYK2, revealing how single amino acid substitutions influence protein abundance, signaling activity, ...
Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or ...
Addis Ababa — African Union (AU) Ministers of Health and Finance, together with Heads of Delegation, have called for urgent and sustained investment in Africa's health workforce, including to build a ...
Virus-associated cancers are a significant and persistent global health challenge, providing unique insight into the relationship between chronic infection ...
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