Aging of the brain is characterized by deleterious processes at various levels including cellular/molecular and ...

Lu]Lu-PSMA-617 radiopharmaceutical therapy has been approved for the treatment of men with metastatic castration-resistant ...

Prostate-specific membrane antigen (PSMA) is a promising target in prostate cancer. Recently, we started the first-in-human treatment with an α-radionuclide–labeled PSMA ligand. Although the case ...

Journal of Nuclear Medicine September 2025, jnumed.125.270267; DOI: https://doi.org/10.2967/jnumed.125.270267 ...

The purpose of this guideline is to assist nuclear medicine practitioners in recommending, performing, interpreting, and reporting the results of brain perfusion imaging to assist in confirming the ...

Journal of Nuclear Medicine October 2025, jnumed.124.269188; DOI: https://doi.org/10.2967/jnumed.124.269188 ...

Immune checkpoint blockade represents a promising approach in oncology, showing antitumor activities in various cancers. However, although being generally far better tolerated than classic cytotoxic ...

Journal of Nuclear Medicine September 2025, jnumed.124.268809; DOI: https://doi.org/10.2967/jnumed.124.268809 ...

Advances in multidetector CT (MDCT) technology with submillimeter slice collimation and high temporal resolution permit contrast-enhanced imaging of coronary arteries and coronary plaque during a ...

Targeting tumors with antibody-based therapeutics is a complex task presenting multiple kinetic barriers. Antibody internalization and clearance inhibit uptake both in solid tumors, limited by tumor ...

High photon attenuation and scatter in obese patients affect image quality. The purpose of the current study was to optimize lutetium orthosilicate (LSO) PET image acquisition protocols in patients ...

Introduction: Deep learning-based denoising have demonstrated potential in reducing noise while maintaining diagnostic performance for myocardial perfusion single photon emission computed tomography ...