Figure 2: Owl monkey cells express a TRIM5–CypA fusion protein that blocks HIV-1 infection. Figure 3: HIV-1 is restricted in human or rat cells transduced with TRIMCyp. Most constructs were previously ...

Researchers at Harvard Medical School have identified a gene in Asian monkeys that may have evolved as a defense against lentiviruses, the group of viruses that includes HIV. The study suggests that ...

Scientists in the U.K. have discovered how poxviruses such as the monkeypox virus (MPXV) and variola viruses evade host cell defenses by exploiting a protein, cyclophilin A (CypA), that puts the ...

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Viruses have many strategies to avoid immune system defenses. They often do this by hijacking the immune system's own proteins. One immune protein that is frequently targeted by viruses, including HIV ...