McNeese has already proven it can compete with powerhouse programs, and Douglas Farmer is taking the points with the Cowboys ahead of their Midwest Region clash.

The No. 12 seed in the Midwest, the McNeese State Cowboys (27-6) begin their pursuit of a Cinderella-run in March against the No. 5 seed, the Clemson Tigers (27-6). The Cowboys won the Southland Conference. The Tigers lost to Louisville in the semifinals of the ACC Tournament.

NCAA Tournament begins its first day of wall-to-wall action on Thursday with first round games from all four regions. Upsets, buzzer beaters and thrilling highlights will fill our day soon, and if your bracket is set to be busted early there's always chances to get back in the action with some best bets.