Please provide your email address to receive an email when new articles are posted on . An investigational anti-MAdCAM antibody was safe, well tolerated and superior to placebo for inducing remission ...
Please provide your email address to receive an email when new articles are posted on . Adult patients with moderate-to-severe ulcerative colitis safely achieved 12-week remission with investigational ...
U.S. FDA Grants Shire Orphan Drug Designation for Investigational Anti-MAdCAM Antibody SHP647 for the Treatment of Moderately to Severely Active Ulcerative Colitis in Pediatric Patients Cambridge, Ma.
Response to immune checkpoint inhibitor (ICI) rechallenge in patients with metastatic renal cell carcinoma who progressed on prior ICI: A systematic review and meta-analysis. Biomarkers of response to ...
Preliminary findings from the first human study of a monoclonal antibody to mucosal adressin cell adhesion molecule (MAdCAM), PF-00547,659, suggest that it might be useful for ulcerative colitis ...
In this Phase 2 study, called TURANDOT, SHP647, the first anti-MAdCAM antibody in clinical development, met its primary endpoint demonstrating significantly greater remission rates in patients ...
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