DFS millionaire Mike McClure shares his top daily fantasy football picks and lineup advice for the Week 6 NFL schedule on Sunday

Discover the best NFL Week 6 prop bets and score big with exclusive sportsbook promos and bonuses. Explore the best NFL player prop bets you can make today!

Keep up with the 2025 NFL season on FOX Sports. Prior to the final injury report, which lists players as questionable, doubtful or out, NFL teams use practice designations to update player injury statuses. This can include DNP (did not participate), LP (limited participant) or FP (full participant).

In this week’s roundup of power rankings across the NFL landscape, the Lions have climbed to No. 1 across every major outlet following their 37-24 Week 5 victory over the Cincinnati Bengals.

One of Kaylor's top DFS picks for Monday Night Football is Chiefs quarterback Patrick Mahomes. The former Texas Tech standout remains an elite fantasy asset with one of the highest scoring floors among all NFL quarterbacks. In 2024, he threw for 3,928 yards with 26 touchdowns.

Stay caught up on all 10 NFL games taking place during the 1 p.m. EDT and 4 p.m. EDT time slots on Sunday, Oct. 5 with NFL RedZone.