CAR T cells with boosted BACH2 protein can fight cancer more effectively

UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes ...

Experimental CAR T therapy targets tumor's immune shield, not cancer cells directly

Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an ...
Science Daily

Scientists solve a major roadblock holding back cancer cell therapy

Researchers have found a reliable way to grow helper T cells from stem cells, solving a major challenge in immune-based ...

Active aldehydes drive T cell exhaustion in the tumor microenvironment, finds study

Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...
The American Journal of Managed Care

Allogeneic vs Autologous CAR T-Cell Therapy Explained

On February 13, Allogene Therapeutics published new long-term follow-up data on cemacabtagene ansegedleucel, showing the investigative allogeneic chimeric antigen receptor (CAR) T-cell therapy ...
FierceBiotech

In 2 papers, Nobel winner debuts technique to turn rogue T cells into their own treatment

Even for a newly minted Nobel laureate, downtime is hard to find. Just a few weeks after winning the 2025 Nobel Prize in Physiology or Medicine for his discovery of regulatory T cells or Tregs, ...