Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...

Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...

Neurons are important, but they are not everything. Indeed, it is "cartilage," in the form of clusters of extracellular matrix molecules called chondroitin sulfates, located in the outside nerve cells ...

Scientists disclose how mitochondria control tissue rejuvenation and synaptic plasticity in the adult mouse brain. Nerve cells (neurons) are amongst the most complex cell types in our body. They ...

A study mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in affected individuals. The researchers showed the role of three proteins in mediating the ...

As animals experience new things, the connections between neurons, called synapses, strengthen or weaken in response to events and the activity they cause in the brain. Neuroscientists believe that ...

This mitochondrial process supports the brain cells essential to learning, memory and social recognition. We know that mitochondria are the powerhouses of the cell, but what role do they play in ...

By adding, removing, strengthening, or weakening synaptic contacts, our brain encodes new events or forgets previous ones. In AD, synaptic plasticity, the brain's ability to regulate the strength of ...

How do we learn something new? How do tasks at a new job, lyrics to the latest hit song, or directions to a friend’s house become encoded in our brains? The broad answer is that our brains undergo ...

Neurodegenerative disease profoundly affects structures and pathways responsible for memory, cognition, and higher-order ...

In a rat model of chronic heart failure, Xijiaqi Formula improved cardiac indices and rescued learning/memory deficits while ...