The results of a new study using mice and heart muscle cells from rabbits have provided a potential molecular explanation for the abnormally rapid heartbeats known as ventricular tachyarrhythmias (VTs ...
Voltage-gated sodium channels (Navs) play essential roles in excitable tissues, with their activation and opening resulting in the initial phase of the action potential. The cycling of Navs through ...
The BACE protease (β-site APP cleaving enzyme) is elevated in the brains of people with Alzheimer disease and takes at least part of the blame for amyloid overload because of its role in the ...
When sodium levels rise too high, it disrupts the release of calcium inside the cells. Calcium release is what triggers the ...
Blood may seem like a simple fluid, but its chemistry is complex. When too much potassium, for instance, accumulates in the bloodstream, patients may experience deadly irregular heart rhythms.
Approximately 2% of patients with irritable bowel syndrome (IBS) have a mutation of the SCN5A gene that disrupts sodium channel function, according to a genotype analysis published online March 10 in ...
This is a preview. Log in through your library . Abstract High resistance epithelia express on their apical side an amiloride-sensitive sodium channel that controls sodium reabsorption. A cDNA was ...
Yale School of Medicine researchers report the first demonstration that a single mutation in a human sodium channel gene can trigger pain in people with an inherited pain syndrome known as primary ...
They're like lightning storms inside the brain. Epileptic seizures blow in suddenly, their rapid and rhythmic electrical bursts disrupting normal brain activity. At the cellular and molecular level, ...
Electrical recordings from mouse neurons revealed differences in how a leading autism gene changes brain signaling before and after birth. Here scientists use pipettes (bright wedges) to record from ...
The results of a study, using mice and heart muscle cells from rabbits, by researchers from Georg-August-University Göttingen, Germany, have provided a potential molecular explanation for the ...
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