Clinical islet allotransplantation has progressed slowly since improved islet-isolation technologies resulted in the achievement of insulin independence in the first series of successful islet ...

Severe chronic pancreatitis is treated by removing the pancreas. Without a pancreas, patients also lose insulin-producing cells called islets. To preserve insulin responses, surgeons transplant islets ...

Detailed characterization of human pancreatic islets is key to elucidate the pathophysiology of all forms of diabetes mellitus, including its most common form known as type 2 diabetes (T2D). However, ...