Senescence describes a nonproliferative state that cells enter in response to various physiological processes or stress and is characterized by prolonged cell cycle arrest and a senescence-associated ...
“Our data show that ADAM19 may be important in mitigating the inflammatory response to intestinal damage and cellular senescence.” “Our data show that ADAM19 may be important in mitigating the ...
A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 16 on August 23, 2024, entitled, "2-Bromopalmitate ...
Senescence is a hallmark of aging, and senescent cells have a reputation to match. They are ‘zombie cells,’ sort of dead themselves but alive enough to poison their surroundings through ...
Aging is marked by a gradual decline in body function, partly driven by the buildup of senescent cells. These cells stop dividing but release a mix of inflammatory and tissue-remodeling factors, known ...
Aged and frail people often suffer a decline in tissue reserve capacity during aging. This reserve, called resilience, helps ...
Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) and aging are locked in a vicious circle: senescence of liver cells accelerates fat accumulation, inflammation and ...
NUDT21 regulates fibroblast senescence and is significantly decreased in aged and fibrotic lungs, impacting IPF progression. Alternative polyadenylation (APA) and NUDT21 downregulation enhance STAT3 ...
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Exosomes carry key indicators of biological aging
A new research paper featured on the cover of Volume 17, Issue 8 of Aging (Aging-US) was published on July 30, 2025, titled "Exosomes released from senescent cells and circulatory exosomes isolated ...
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