The first step to understanding an RBP's roles is to identify the RNAs it interacts with. The development of HITS-CLIP and iCLIP methods revolutionized our ability to map RBP binding sites in vivo by ...
In a recent study published in Nature, a group of researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into messenger ribonucleic acids (mRNAs) affects ribosomal ...