A mechanistic understanding of the cell requires the structural characterization of the thousands of its constituent biological assemblies 1. So far, conventional approaches have provided a valuable ...

Scientists have engineered a protein able to record the incoming chemical signals of brain cells (as opposed to just their ...

We propose that the forward and reverse halves of a flash-induced protein-protein electron transfer (ET) photocycle should exhibit differential responses to dynamic interconversion of configurations ...

Scientists report two new cryo-EM structures representing the pre- and postfusion conformations of the full-length SARS-CoV-2 spike (S) protein, an essential viral component responsible for host cell ...

The active sensing site of GPR4 is made up of histidine residues (Figure 1). 2 This is of particular interest, given that the dissociation constant representing the dissociation of histidine protons ...

Scientists are closing in on a deceptively simple idea with radical implications: that a single protein signal in the blood ...