Prion diseases are a group of different conditions that affect your brain and nervous system. They can cause severe dementia or problems with body control that get worse very quickly. They're rare -- ...

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP. How these aggregates form ...

New research from Japan suggests that a rare brain-destroying disease caused by rogue prion proteins may be becoming more common—likely due to an aging population. The study, published last month in ...

Prion diseases are rare and occur due to proteins in the brain that “misfold.” Another name for prion disease is transmissible spongiform encephalopathies (TSEs). There are many types of prion ...

Close-up on three ropes and marine knots isolated on white background. Each is photographed separately. Prion diseases are rare but deadly neurodegenerative brain diseases that result from misfolding ...

August 24, 2010 — A novel sporadic prion protein disease, variably protease-sensitive prionopathy (VPSPr), with distinct features has been described as the first new prion disease since sporadic ...

The center is supported by the CDC and sponsored by the American Association of Neuropathologists. The National Prion Disease Pathology Surveillance Center (NPDPSC) is the only Center of its kind in ...

The misfolded proteins responsible for a fatal neurological illness in deer have a twist. The first detailed structure of an infectious prion that causes chronic wasting disease, or CWD, reveals ...

For many years, the only antemortem clinical laboratory test available for prion disease was limited to the detection of 14-3-3 and total Tau proteins in CSF. As rapid neurodegeneration is a hallmark ...

Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death. Although the causal link between protein aggregates and ...