Far from a static barrier, the brain’s extensive interface with the blood is increasingly being appreciated as an active border, one that serves not only to keep some proteins out, but to let others ...

Scientists uncover key proteins driving brain aging, offering critical insights into timing interventions to preserve brain health and combat neurodegenerative disorders. Study: Plasma proteomics ...

Some people’s brains age faster than average, some slower. Scientists quantify this “brain age gap” by subtracting a person’s chronological age from their brain’s biological age. Because aging brains ...

A multi-institutional team led by the Chinese Academy of Sciences has constructed a proteomic atlas of human aging across 13 organs, revealing tissue-specific aging clocks, transcriptome-proteome ...

It has long been appreciated that dynamic non-genetic factors, including external factors such as diet, lifestyle, environment, and toxicants, as well as internal factors including organ physiology, ...

Proteins are essential macromolecules that play a crucial role in virtually all biological processes. They are the building blocks of life, performing a wide range of functions within organisms, from ...