One of the most comprehensive ocular pharmacokinetic studies including metabolism so far provides valuable information for ocular drug development. Severe visual illnesses are increasing in our ...

Severe visual illnesses are increasing in our society, and effective treatments are missing for diseases as age-related macular degeneration, diabetic retinopathy, and glaucoma. Both industry and ...

Neurodegenerative disorders are pressing global health challenges that stem from progressive neuronal dysfunction and loss. While the central roles of ...

Protheragen has expanded its 13C/14C-labeled compound portfolio to support research in metabolic pathways, pharmacokinetics, breath assays, and biochemical tracing. The expanded lineup improves ...

Mice are frequently used as models to test novel candidate compounds during drug discovery and development. However, many compounds show efficacy against the drug target in vitro but present poor ...

In a study posted to the bioRxiv* preprint server, researchers studied the preclinical pharmacokinetics (PK) and in vitro absorption, distribution, metabolism, and elimination (ADME) properties of ...

Developing high-quality, safe, and effective drugs is a complex process that requires varied scientific skills and stringent regulatory assessments. Drug development is a process that spans many years ...

It has always been known that biological females and males have different body compositions. For example, men typically are larger, have more muscle, and weigh more than women in humans, a trend seen ...