Northwestern Medicine investigators have uncovered new insights into how metabolic dysfunction contributes to Parkinson's ...

“Prior studies have revealed mitochondrial dysfunction to be a driver of Parkinson’s disease, but the molecular mechanisms through which mitochondrial metabolic pathways contribute to the pathogenesis ...

THE GLOBAL prevalence of Parkinson’s disease is projected to more than double by 2050, reaching 25.2 million cases, with ...

Researchers say structure reveals many new ways to change PINK1, essentially switching it on, which will be "life-changing" for people with Parkinson’s disease.

This observation suggests that Prx2 has a functional role in the pathogenesis of sporadic Parkinson's disease. One possibility is that the loss of Prx2 activity induces neurodegeneration through ...

A new study published in Cell Reports reveals a breakthrough discovery linking genetic variants in the gene ITSN1 to a ...

Understanding the pathogenesis of LID has contributed ... of dyskinesia as a motor complication in the course of Parkinson's disease (PD) includes a spectrum of involuntary movements schematically ...

This recent study highlights the neuroprotective potential of TFE3, a transcription factor that plays a pivotal role in ...

Clinical diagnosis of Parkinson's disease (PD) could be performed in ... and serotoninergic systems has been implicated in the pathogenesis of depression in PD. They have been associated with ...