The histopathology of RNs is defined by 3 stages: acute inflammation, granulation, and necrosis. The lesions develop from small areas of granulated tissue into large nodules with necrotic centers.

Scleroderma is a rare autoimmune disease involving an overproduction of the protein collagen. Linear scleroderma usually begins as a streak of hardened, waxy, discolored skin on the forehead, an arm, ...