Secondary efficacy analyses of the pivotal SEQUOIA-HCM trial continued to favor aficamten, supporting a potential role for another cardiac myosin inhibitor in obstructive hypertrophic cardiomyopathy ...

A 35-70% ammonium sulfate fraction of smooth muscle actomyosin was prepared from guinea pig vas deferens. This fraction also contains a smooth muscle myosin kinase and a phosphatase that ...

Motor proteins belonging to the myosin family are among the best understood molecular machines. Myosin motor domains are accessible for analysis by an exceptionally wide range of experimental ...

This is a preview. Log in through your library . Abstract Antibody against cytoplasmic myosin, when microinjected into actively dividing cells, provides a physiological test for the role of actin and ...

Edgewise Therapeutics Inc. has divulged pyridazinone compounds acting as myosin-2 (MYH2) (ATPase activity) inhibitors reported to be useful for the treatment of Duchenne muscular dystrophy, ...

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