I always use a second SSD for my game installs (although technically I have three other SSDs with games on, because I hate re-downloading them), and I think everyone should. It's not about performance ...
Selecting the correct M.2 slot for your NVMe SSD is crucial for maximizing performance and avoiding potential damage to your drive or motherboard.
Though limited by motherboard bifurcation capabilities (4x4x4x4 is required for all four slots to operate), the Hyper M.2 x16 ...