The tumor microenvironment (TME) represents a highly complex system that encompasses cellular components (such as cancer cells, stromal cells, and immune cells) and non-cellular components (such as ...

Cancer cells survive therapy by dynamically rewiring their metabolism in response to nutrient availability, ...

FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

Cancer cells continuously interact with their surrounding microenvironment, critically influencing tumor development, metastasis, immune evasion, and therapy resistance. Metabolic reprogramming in ...

A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune ...

Scientists have uncovered how a vitamin A metabolite can suppress anti-cancer immunity. Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have uncovered new ...

Researchers found in mice that multiple nutrients and cancer cell characteristics work together to control the spread of ...

The field of cancer immunology has witnessed dramatic progress with the advent of immunotherapies targeting the tumor immune microenvironment (TIME).

A research paper by scientists from Beijing Institute of Technology investigated the anti-tumor effect of millimeter waves ...

In recent years, cancer immunotherapy has transformed the treatment landscape for a wide range of malignancies, offering ...

A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune response in five preclinical ...