Organs often have fluid-filled spaces called lumens, which are crucial for organ function and serve as transport and delivery ...

Organs often have fluid-filled spaces called lumens, which are crucial for organ function and serve as transport and delivery ...

Pancreatic organoids reveal how lumen shape is controlled by the balance between cell proliferation, internal pressure, and epithelial permeability.

Working with three-dimensional pancreatic models (organoids), derived from mouse cells, researchers combined computer simulations with experiments to find out what controls the shape of lumens ...

We discuss the physical mechanisms that promote or suppress the nucleation of a fluid-filled lumen inside a cell assembly or a tissue. We discuss lumen formation in a continuum theory of tissue ...