Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...
Why does the COVID-19 virus make some people sicker than others? For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There ...
Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have ...
Global trends and regional disparities in young-onset breast cancer: Age-specific patterns from 1990 to 2021.
In the study, "MTAP deficiency confers resistance to cytosolic nucleic acid sensing and STING agonists," published in Science, researchers designed a series of molecular and in vivo experiments to ...
Duke Health researchers found a relationship between immune response and neurological behavior after studying mice with a specific gene mutation, which exhibited signs of ADHD in response to an ...
Research presented by Professor Cecilia Johansson of Imperial College London has linked early type I interferon signalling in ...
Intracellular Delivery via EV-based Approach (IDEA) was designed to efficiently package and deliver non-fused intracellular proteins to cytoplasmic or nuclear compartments to be functional. As a ...
The idea that infiltrating T cells contribute to a neurodegenerative environment in aging and in Alzheimer’s disease has gotten another boost. In the June 27 Nature Neuroscience, scientists led by ...