Representative cryo-electron microscopy image: a coloured image of the 3D structure of gephyrin, which was calculated from the data. A team of scientists from the University of Cologne’s Institute of ...

Using a mouse model, researchers have discovered a new daily rhythm in a type of synapse that dampens brain activity. Known as inhibitory synapses, these neural connections are rebalanced so that we ...

Using a mouse model, researchers have discovered a new daily rhythm in a type of synapse that dampens brain activity. Known as inhibitory synapses, these neural connections are rebalanced so that we ...

Whether picking up a small object like a pen or coordinating different body parts, the cerebellum in the brain performs essential functions for controlling our movement. Researchers investigated how a ...

The regulation of neuronal excitability and the maintenance of an appropriate balance between excitation and inhibition are central to brain function. Inhibitory synaptic transmission, predominantly ...

Endophilin A1 at postsynaptic sites promotes inhibitory postsynaptic organization through interaction with gephyrin to maintain E/I balance, which is essential for the suppression of epilepsy ...

Memory, a fundamental tool for our survival, is closely linked with how we encode, recall, and respond to external stimuli. Over the past decade, extensive research has focused on memory-encoding ...

An international team of researchers led by scientists at UC San Diego School of Medicine have shown that the virus which causes COVID-19 can damage brain cell synapses, according to a report ...