Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...
Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct structures of the chromatin remodeler SNF2H offering a comprehensive view the ...
The framework of CASHeart. (A) Overview of the data collection and data processing workflow in the CASHeart Database. (B) Introduction to the main interfaces of the CASHeart website. The human heart ...
It is still not fully understood how, despite having the same set of genes, cells turn into neurons, bones, skin, heart, or roughly 200 other kinds of cells, and then exhibit stable cellular behavior ...
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Jumping genes reshape cancer genomes through 3D chromatin interactions
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.
Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...
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