Using human-induced pluripotent stem cell-derived kidney organoids, researchers from Science Tokyo uncovered how abnormal Hippo signaling drives fibrosis in nephronophthisis, a genetic kidney disorder ...

The liver's ability to communicate with other organs is crucial for maintaining homeostasis, particularly through signaling pathways. During liver regeneration, communication with organs such as the ...

CYR61, cysteine-rich angiogenic inducer 61; FT, factors of transcription; LATS, large tumor suppressor; MOB, mob kinase activator; MST, mammalian sterile 20-like ...

The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study. Researchers focused on a group of interacting genes called the Hippo pathway, which serve as ...

Prognostic role of platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) in advanced gastric cancer treated with immunotherapy: A systematic review and meta-analysis. This is an ...

A recent article posted to the bioRxiv* preprint server illustrated that the activation of the Hippo signaling pathway upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection aids ...

A new study describes the formation of the body axis in the immortal freshwater polyp Hydra. This is controlled by the so-called hippo signaling pathway, a molecular biological process that, among ...

Two seemingly disparate signaling pathways -- one that controls organ size in fruit flies and another important for the growth of embryos -- interact in embryonic mouse hearts to restrict cell ...