The bacteria that cause food poisoning, bubonic plague, and whooping cough all deploy the same weapon to infect the body. A molecular "syringe" sticks out of the bacteria, pokes a hole in a nearby ...

Scientists at Duke University report they have developed a synthetic antibiotic that could be effective against drug-resistant superbugs and bacteria such as Salmonella, Pseudomonas, and E. coli.

In natural environments, bacteria rarely live as free-swimming cells but are attached to surfaces as biofilms in medical ...

An antibiotic called thanatin attacks the way the outer membrane of Gram-negative bacteria is built. Researchers have now found out that this happens through a previously unknown mechanism. Thanatin, ...

Gram-negative meningitis is a form of meningitis. The term gram-negative refers to a way of differentiating bacteria. This type of bacteria is typically resistant to drugs and most available ...

LpxC inhibitors target a zinc-dependent deacetylase that catalyses the first committed step in lipid A biosynthesis, an essential process for the viability of Gram-negative bacteria. As lipid A forms ...

The last antibiotics generated against Gram-negative bacteria—which tend to be the more dangerous type—were developed in the 1960s. Thanks to the rise of antibiotic resistance, we need more. But ...

For decades, pharmaceutical companies have been using bacteria found in soil and water to chemically convert steroids into ...

Results from a phase 2 randomised trial suggest that a new investigational antibiotic is as effective as the current standard-of-care antibiotic for the treatment of complicated urinary tract ...