Figure 1: Design of double-cysteine mutants of the 380-kDa dynein motor domain for disulfide cross-linking between the two helices of the stalk coiled coil. These studies, especially the helix-sliding ...
Dyneins are large microtubule-based motors that power a wide variety of cellular processes. Here we report a 4.5-Å X-ray crystallographic analysis of the entire functional motor domain of cytoplasmic ...
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