Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three ...

Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic ...

Over the years, cell biology has built a detailed picture of how cells compartmentalize their internal functions. Central to this organization is the nucleus, which houses the genetic material and is ...

More than 200 metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study published in ...

Scientists discovered hundreds of energy-making enzymes secretly working on human DNA—revealing a hidden “mini-metabolism” ...

Scientists have found DNA in the nucleus of brain cells, where it shouldn’t be. Bits of genes that typically reside in mitochondria insert themselves at unexpectedly high rates into brain cells’ ...

Researchers have found evidence of nuclear metabolic enzymes for the first time, contributing to our understanding of cancer ...

By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...

Cells were long believed to safeguard nuclear contents, releasing them only during cell death. Extracellular DNA was thought ...