An October chill has reached the Lehigh Valley, which is typically an indicator that the schedule is filled with important football games. Find predictions for all of the weekend’s contests below as programs battle for division title contention and postseason berths.

Cardinals vs. Colts (-5.5), Browns vs. Steelers (-5.5), Chargers vs. Dolphins (+4.5) and Titans vs. Raiders (-4.5) are some other games with a line more than four points to consider for NFL survivor picks. Before finalizing any Week 6 NFL survivor picks, see which team the red-hot SportsLine Projection Model just went all-in on.

After Week 6 proved more chaotic than we expected, we'll see if we get the same result in Week 7, which is headlined by a top-10 Big Ten matchup.

College football Week 7 odds, picks, predictions, TV channel, streaming for Pittsburgh Panthers vs Florida State Seminoles ACC game on Oct. 11, 2025.

This looks like a telltale game for Garber. The Dukes are coming off a brutal four-game stretch in which they not only lost each outing but paid a steep cost with injuries. This is a matchup they can win – and did win 21-7 a year ago – but are they able-bodied enough to do it? Alma 14, Garber 12