Diffuse intrinsic pontine gliomas (DIPGs) carry an extremely poor prognosis. Standard practice has been to base the diagnosis on classic imaging and clinical characteristics and to treat with focal ...

Like other tumors that arise in midline structures of the brain, most DIPGs are histone H3-mutated tumors that harbor H3K27M mutations. DIPG typically originates in the ventral pons, which is the ...

Partial or total resection appeared associated with longer OS compared with biopsy alone among a cohort of adults with brainstem high-grade gliomas, according to study results published in Journal of ...

A glioma is a type of brain tumor that forms from glial cells. These cells support and protect neurons in the brain. There are many types and subdivisions of gliomas. Gliomas are the most common type ...

Fractionated reirradiation is safe for recurrent high-grade glioma, with a median dose of 41.4 Gy and no critical structure injuries observed. Improved overall survival correlates with better ...