AUGUSTA, Ga. (May 30, 2023) – It sounds like bile acid in the eye would hurt, but scientists think stimulating one of its receptors can actually help protect the vision of premature newborns. It’s ...
The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism. Bile acids are natural ligands of FXR, which bind to the ...
Scientists have known for some time that gut bacteria modify bile acids into a form that stimulates a receptor called FXR, ...
Hepaitech (Beijing) Biopharma Technology Co. Ltd. has disclosed bile acids acting as farnesoid X receptor (FXR) and/or G-protein coupled bile acid receptor 1 (GPBAR1; TGR5; GPCR19; GPR131) agonists ...
The study details the connection between SCARB2 deficiency and gastrointestinal dysfunction, revealing that the loss of SCARB2 leads to alterations in bile acid metabolism and dysbiosis in the gut ...
Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect ...
A study published in the journal Cell Metabolism finds that hyodeoxycholic acid alleviates non-alcoholic fatty liver disease by modulating the gut-liver axis. Study: Hyodeoxycholic acid alleviates non ...
Bile acids, synthesised from cholesterol in the liver, are central to lipid digestion but also serve as signalling molecules that regulate metabolism, inflammation and cellular homeostasis. In ...
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