Figure 1: Bisindolylmaleimide VIII enhances apoptosis induced by anti-Fas antibody in 1321N1 cells. Apoptotic cell death of 1321N1 cells treated with both anti-Fas antibody and bisindolylmaleimide ...

The cytostatic and cytotoxic effects of doxorubicin on the cells were assessed with MTT assay as described above. Attached cells were incubated with different doses of doxorubicin for 24 hours.

A new study has discovered a promising approach to improve the efficacy of adoptive cell therapies for cancer. The research, published in Molecular Therapy: Nucleic Acids, describes the development of ...

Scientists have made a novel discovery about how gene, "Fas-apoptosis inhibitory molecule", protects both immune and liver cells from programmed cell death. Scientists at Singapore's Bioprocessing ...

HAART influences the presenting characteristics and improves the outcome of patients (pts) with Hodgkin’s disease and HIV infection (HD-HIV) No significant financial relationships to disclose. This is ...

Papillomaviruses are small DNA tumor viruses that infect stratifying epithelial tissues and cause warts. Specific types of human papillomaviruses (HPV), termed ‘high-risk’ types, infect the mucosa of ...

Analysis of immune infiltrates in a genomically characterized clinical cohort of head and neck squamous cell carcinoma (HNSCC) patients (pts).

The deposition of Aβ has long been implicated in the cellular damage and subsequent cognitive dysfunction of Alzheimer's disease, but the mechanism for this remains unclear. Recently, evidence has ...

It appears that a particular cell-death pathway can be restricted to one class of neurons, suggesting a mechanism for the specificity of neuronal death in diseases ranging from ALS to Alzheimer's. In ...

Scientists at Singapore's Bioprocessing Technology Institute (BTI) have made a novel discovery about how the gene, "Fas-apoptosis inhibitory molecule" (FAIM), protects both immune and liver cells from ...