The study of experimental evolution in Escherichia coli has provided unprecedented insights into the mechanisms of adaptive mutations, elucidating how populations diverge and optimise their fitness ...

In real life, mutants can arise when their DNA changes to give them an advantage over the rest of the population. A team from ...

A groundbreaking study published in this week’s issue of PNAS by scientists from Israel and Ghana shows that an evolutionarily significant mutation in the human APOL1 gene arises not randomly but more ...

Vaccinating birds against bird flu reduces the spread of the disease, but may have unintended consequences. This is the warning of a new paper in the journal Science Advances, which concluded that ...

All of living nature is subject to evolution. Living organisms are exposed to selection pressure, which means that those that are best able to assert themselves survive. This natural selection process ...

Researchers published a new study, “Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution,” in Cell that they say solves the mystery of what drives the genomic ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 possible variants—more combinations than atoms in the observable universe.

Mitochondria are known as the body’s “energy factories,” and their function is essential for life. Inside mitochondria, a set of complexes called the oxidative phosphorylation (OxPhos) system ...

KRAS is the most frequently mutated oncogene across all human cancers. Although different KRAS mutations have long been thought to exert the same cancer-driving effects, a new study led by UT ...

This year’s Sjöberg Prize of one million US dollars is awarded to a British cancer researcher who has provided fundamental knowledge about evolution in tumours. Charles Swanton, at the Francis Crick ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.