Spliceosomal introns are noncoding DNA sequences located between exons in many eukaryotic protein-coding genes. Most are ...

Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication is initiated in eukaryotes. Using Vanderbilt's state ...

Eukaryotic DNA replication relies on a highly orchestrated series of events centred on the Cdc45–MCM–GINS (CMG) helicase complex. Origin licensing begins in G1 phase with loading of a double hexamer ...

Mechanisms for replicating DNA / G.S. Brush and T.J. Kelly -- Origins of DNA replication / M.L. DePamphilis -- Roles of transcription factors in DNA replication / P.C. van der Vliet -- Roles of ...

For foreign DNA to make it into a eukaryotic cell’s genome, DNA must first enter the cell, then cross the nuclear envelope, and finally insert itself into the genome. Below are a number of proposed ...

Prokaryotes are ancient, simple forms of life that include bacteria and archaea. These cellular life forms lack membrane-bound organelles. Those organelles, which include the nucleus and the ...

A new study challenges a popular scenario put forward to explain the arrival of the first eukaryotic organisms. In the beginning, there was boredom. Following the emergence of cellular life on earth, ...