As the gradient decays, the position of this threshold value moves at varying speed along the membrane, depending on the cell shape. Thus, via this hierarchy of protein concentration profiles, the ...

a) A classical morphogen (pink) elicits differential gene expression (represented by the black, red and blue bars) by activating different genes at different concentrations. b) One example of such a ...

Morphogens are signaling molecules that are released from particular areas of tissues, creating a concentration gradient that decreases in concentration further away from the source. This has ...

Scientists know that physical and biochemical signals can guide cells to make, for example, muscle, blood vessels or bone. But the exact recipes to produce the desired tissues have proved elusive. Now ...