Cells working with an expanded genetic code could make more diverse medicines. A new study shows scientists are within striking distance. One of modern biologists' most ambitious goals is to learn how ...
Dengue is the most prevalent mosquito-borne viral disease in the world. Globally, about half of the world’s population is now at risk of dengue with an estimated 100–400 million infections occurring ...
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...
Short stretches of rare codons regulate translation of the transcription factor ZEB2 in cancer cells
Two proteins comprising the ZEB family of zinc finger transcription factors, ZEB1 and ZEB2, execute EMT programs in embryonic development and cancer. By studying regulation of their expression, we ...
Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...
61 codons specify one of the 20 amino acids that make up proteins 3 codons are stop codons, which signal the termination of protein synthesis Importantly, the genetic code is nearly universal, shared ...
A new examination of the way different tissues read information from genes has discovered that the brain and testes appear to be extraordinarily open to the use of rare codons to produce a given ...
The genetic code — the rules by which codons are translated into amino acid sequences — is almost universally conserved across all domains of life, although a minority of species are now known to use ...
When a ribosome cruises along messenger RNA (mRNA), it may stall at a particular codon, depending on which codons are nearby. In other words, codon context can influence the efficiency with which mRNA ...
The bacteria happily eating and reproducing and respiring in little plastic dishes sprinkled with nutrient broth in Jason Chin’s lab outside London look ordinary enough, but they differ in a ...
DURHAM, N.C. -- A new examination of the way different tissues read information from genes has discovered that the brain and testes appear to be extraordinarily open to the use of many different kinds ...
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